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34+ Defiance Holiday Rentals & Private Villas

Find Family-Friendly Holiday Rentals in or near Defiance

Discover more than 34 holiday rentals in Defiance. Casai holiday homes have everything you need to find a place to stay near Defiance, MO.

Whether you are looking for luxury villas in Defiance, furnished homes, unique style condos, flats, cozy cottages for a romantic getaway, spacious apartments for family holidays, or stylish accommodations for a business trip, we can help you find the perfect place. Our holiday rentals include top amenities such as indoor/outdoor swimming pools, kitchen facilities, gyms, hot tubs, Internet connectivity, and more.

If you are planning to travel to Defiance with a whole family or group, Casai holiday accommodations will make your trip memorable. We have plenty of places to stay in Defiance for families, large parties, or private owner accommodations for long or short trips. Defiance Pet-friendly holiday rentals are available. Book your favorite vacation rentals in Defiance with Casai. Casai makes it easy to compare and book holiday rentals today.

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Frequently Asked Questions About Defiance Holiday Rentals

There are a lot of options in Defiance. If you plan on staying in the Defiance area, consider making a reservation for a few nights at one of these properties as these have been rated the top Holiday Home Rentals in Defiance:

There are many holiday rentals available in Defiance; however, here are a few of the most popular holiday homes listed in Defiance on our website:
At Casai.com most of our places to stay are perfect for families. Check out the complete list of holiday homes in Defiance to find one that works for you.
Yes, there are 34 self-catering family homes and holiday rentals in Defiance.
There are more than 34 luxury holiday homes in or near Defiance, according to 2025 data from Casai.com. Consider these homes for your next holiday:
Yes, there are 34 pet friendly rentals that are available in Defiance.